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Best Known Method By Keyto Podcast

Best Known Method is a podcast where host Ethan J. Weiss asks some of the most successful people how they approach making life’s most important decisions – all with less than perfect information to guide them.

01 – Sid Mukherjee: The Napkin Moment

Sid Mukherjee, Indian-American physician, biologist, oncologist, and best-selling author, joins the Best Known Method to speak with host Ethan J. Weiss about his journey to studying at Stanford, Oxford and Harvard, becoming one of the great physician-writers of this time, and his recent research into the effect of the ketogenic diet on cancer.



02 – Ron Krauss: The Pattern Guy

Dr. Ron Krauss, Senior Scientist and Director of Atherosclerosis Research at Children’s Hospital Oakland Research Institute, joins the Best Known Method to speak with host Ethan J. Weiss about his life-long interest in cardiovascular disease, writing and subsequently re-writing the nutrition guidelines for the American Heart Association, and the relationship between diet and nutrition, and risk of cardiovascular disease.


03 – Eric Topol: The Optimistic Futurist


04 – Jessica Mega: The Data Doctor

Jessica Mega, Chief Medical and Scientific Officer at Verily, joins the Best Known Method to speak with host Ethan J. Weiss about the influence of the Yale system on her leadership ethos, a career switch from Harvard to Google, and how she approaches medical research as part of the world’s largest search engine.


05 – Roger McNamee: The Instrumental Technologist

Roger McNamee, philanthropist, investor, venture capitalist and musician, joins the Best Known Method to speak with host Ethan J. Weiss about his great success as an early investor in tech startups such as Facebook and Yelp, and what led to him writing Zucked: The Education of an Unlikely Activist, a book warning about the dangers consumers face from many of these same companies.


06 – Rob Lustig: The Unsweetened Truth

Dr. Robert Lustig, Professor of Pediatrics in the Division of Endocrinology at UCSF and author, joins the Best Known Method to speak with host Ethan J. Weiss about how he shifted his research focus from the sex differentiation of the brain, to how the brain controls eating. Through this work, Rob became an outspoken researcher and activist on the obesity epidemic, and a strong critic of processed sugars.


07 – Lisa Rosenbaum: Writing From The Heart

Dr. Lisa Rosenbaum, cardiologist on the faculty of Harvard Medical School and the Brigham and Women’s hospital, and National Correspondent for New England Journal of Medicine, joins Best Known Method to speak with host Ethan J. Weiss about her storied career, split between the roles of physician and writer.


08 – Sek Kathiresan: The Inherited Mission

Dr. Sek Kathiresan, CEO of Verve Therapeutics, joins Best Known Method to speak with host Ethan J. Weiss about his experiments to map the areas of our genome that are associated with different levels of blood cholesterol, the genetic basis underlying risk of heart attack, and his decision to step away from his roles as Director of the Center for Genomic Medicine at Massachusetts General Hospital, Director of the Cardiovascular Disease Initiative at the Broad Institute, and Professor of Medicine at the Harvard Medical School, to put all of his efforts into Verve.